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Moreover, the reference list of selected papers was checked manually to include some high-impact additional studies from the bibliography of the original papers or meta-analyses that were relevant to the topics addressed (Figure 1)

Apart from the mitochondria, the containment of highly acidic enzymes within the lipid-membrane boundary of lysosomes requires the CoQ 10 -induced intermembrane proton gradient [8,43]

This dual action is what sets it apart from standard GLP-1 drugs like semaglutide

The scientific community emphasizes the need to conduct controlled clinical studies to validate the promising preclinical observations